A Stratified Flow-driven Route to Monodisperse Unilamellar Lipid Vesicles

نویسندگان

  • S. Matosevic
  • B. M. Paegel
چکیده

Giant unilamellar vesicles (GUVs) are good models of living cells, owing to their size and lamellarity. Compartmentalization within lipid vesicles has been exploited for the study of membrane behavior, lipid mechanics and a variety of biological processes, though their synthesis is not straightforward. We describe the development of a stratified flow driven microfluidic approach to GUV assembly that will afford control over size, lamellarity and membrane composition.

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تاریخ انتشار 2010